Ok this guide is going to show you how I soloed Fissure of Woe and got some uber drops. I was a Warrior/Monk though.
Just to give you an overview my stats looked a little something like this:
9+2 Axe Mastery, 11 Healing Prayers
1 Strength, 8 Tactics, 9 Smiting Prayers
Once you have these stats around there or so then you should get these skills.
Mending- While you maintain this "Enchantment", target ally gains health regeneration of +1-3.
Live Vicariously- While you maintain this "Enchantment", whenever target ally hits a foe, you gain 1-11 health.
Balthazar's Spirit- While you maintain this "Enchantment", target ally gains adrenaline and Energy after taking damage. (The amount of adrenaline gained increases depending on your rank in Smiting Prayers.)
Balthazar's Aura- For 10 seconds, foes adjacent to target ally take 10-22 holy damage each second.
Symbol Of Wrath- For 5 seconds, foes in this location take 8-27 Holy damage each second.
CycloneAxe- Perform a spinning axe attack striking for 4-10 more damage against all adjacent opponents.
Bonetti's Defense- For 5-10 seconds, you have a 75% chance to block incoming melee attacks. You gain 5 energy for each successful melee attack blocked. Bonetti's Defense ends if you use a skill.
Healing Signet- You gain 40-130 health. You have -40 armor while using this skill.
By the look of the skills you can pretty much tell what you are going to be doing bu just in case you can't here it is :
You are going to get into FoW alone (1 whole plat)
Set by putting Mending on, then Live Vicariously then right before you aggro Balthazar's Spirit( you want to cast blathazars last because you will have mana degen of -1. But, once you aggro and start getting hit you will regain the mana)
Here's a list on what to do.
1. Mending
2. Live Vicariously
3. Balthazar's Spirit
4. Cyclone Axe
5. Bonetti's Defense
6. Aura of Balthazar
7. Cyclone Axe
8. Bonneti's Defense
9. Symbol of Wrath
10. Rinse and Repeat until not needed
So you hit cyclone axe which heals you for 11 times X the people you hit.
Then Bonneti's to cut the damage and get mana waaay faster. Then nuke, Cyclone to heal Bonettis to cut dam. Symbol of wrath to nuke some more..Once again, Rinse and Repeat.
P.S. You can nuke more frequently if you like, i did it like that too be safe kinda like Mountain Trolls just waay harder
Good luck Heres a screen shot of me about to die becasue i nuked to close together but i actually made it 
*Edit*
Yeah the Ether dudes own but you just have kill em as quick as fast. Aura of Balthazar pretty much owns expecially cus they are undead. hope htis helps
*ok here is to answer all the questions!!!*
1. Wear Gladiators armor. less defense but only by a little bit and its +20 against physical damage.
2. Use a shield to boost ur defense, maybe use an offhand ahkn if you want but it will make make your defense even lower.
3. A for spiteful spirit just try and keep your health up as best you can.
4. Im not sure maybe i did get lucky but i can usually do it following this guide.
