Speed up attacks by skipping animation : City of Heroes - Submissions

You can partially to fully override all kinds of character animations including character powers by performing them mid-jump. For instance using a normal ranged attack as a blaster such as fire blast, if you hit the power hotkey then immediately tap the spacebar while in midrun, your character will cast in mid air WHILE still running. You can tap spacebar to jump and override buff powers and inspiration uses in midrun. This is most effective with powers that don't have long animations. Mastering this skill gives a big advantage in combat as you are able to avoid many more melee attacks, chase/attack at the same time, etc