Hover, Never Be Attacked : City of Heroes - Submissions

Must have ranged attacks, blaster works best. If you can get some enhancements, it would make killing easier.

Go somewhere that is closed off and has a high ceiling. Hover up into the air, and begin to shoot at the mob. You'll be able to hit them, but they wont be able to hit you.

The mob has to have limited range attack. Mobs like the Man O War (Perez Park, in the Lake.), and the Ebalmed Cadaver (Vahzilok), work great.

This generally will only work with Sniper Attacks. But the AI is programed to run away if you are out of range. This was a big tactic during Beta but was quickly countered by making sure all Mobs have a ranged attack.