There is an awesome hack going around right now and it has to do with stacking runes in the game. Basically they made it so you can edit the memory values for runes stacked which has lead to people have zero cool down times on everything, extra damage, and more. Basically you are in god mode with this exploit. Anyways here is how you do it.
Just download cheatengine - google search
Then change your masteries to 24/4 ect with cheat engine.
(!empty($user->lang['QUOTE'])) ? $user->lang['QUOTE'] : ucwords(strtolower(str_replace('_', ' ', 'QUOTE'))):
1-Open cheat engine -> click the pc icon -> choose the LoL process
2-Put 0 and click First scan
3-Put 1 for example on swiftness
4- Go to Cheat engine -> Put 1 -> Next scan
5- Put 2 on swiftness
6- Go to cheat engine -> Put 2 -> Next scan
7- Click the code that appears on the left of Cheat Engine
8- Change the value for the remaining points you have (if its swiftness 23)
9- Save mastery Page on LoL
10- Done.
You can now add extra masteries.
Example Image