Here's a chest run that not many people know about. Leave the Sanctum Cay staging area out the north gate. From here, work your way northwest past all the Bog Skales to the south tip of the lake in the middle of this zone. From here you should see anywhere from 1-3 chests that spawn randomly in this area. One of them contains around 100 gold, which is a nice bonus, but the real prize is the other two chests. Those drop anywhere from 1-4 items, and have very good chances of dropping purples and golds. You'll average maybe one gold every 5 chests. These items are of all types, so you'll get all sorts of good weapon upgrades and occasionally a top rare weapon, including the valuable models like Crystalline Swords.
This run is a pain. There are a lot of Bog Skales between you and the chest, and they all spam Chilblains and other debuffs. You're either going to need a lot of stacked enchantments and speed boosts to farm these, or the patience to kill the mobs on your way there.
